Research Article
Evaluation of Analgesic Activity of Papaver libanoticum Extract in Mice: Involvement of Opioids Receptors
Table 6
Analgesic activity of PLE by acetic acid induced writhing in mice.
| | Group | Number of writhes (mean ± SEM) | Reduction in writhes count (%) |
| | Control (acetic acid 1%) | 59.6 ± 6.5 | 0% | | Diclofenac 10 mg/kg | 29.6 ± 3.9 | 50% | | Morphine 5 mg/kg | 3.2 ± 0.8 | 95% | | PLE 100 mg/kg (prior 30 min) | 25.4 ± 3 | 57% | | PLE 100 mg/kg (prior 3 hrs) | 31.6 ± 3 | 47% | | Naloxone + PLE (prior 30 min) | 23.4 ± 2.4 | 61% |
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