Pharmacokinetics of Caffeic Acid, Ferulic Acid, Formononetin, Cryptotanshinone, and Tanshinone IIA after Oral Administration of Naoxintong Capsule in Rat by HPLC-MS/MS

Table 2

Linear regression data, LLODs, and accuracy for the eleven compounds.

Compounds	Regression equation		Linearity range (ngmL^−1)	LLOD (ngmL^−1)	Accuracy (%)	RSD (%)
Paeoniflorin		0.9997	2.5–750	2.5	99.5	13
Ecdysterone		0.9985	5–1500	5	100	6.3
Amygdalin		0.9976	10–3000	10	99.2	12
Mulberroside A		0.9910	3–3000	3	92.3	14
Caffeic acid		0.9993	3–3000	3	100	7.4
Ferulic acid		0.9962	1.5–1500	1.5	91.4	5.4
Salvianolic acid B		0.9972	10–3000	10	105	7.8
Astragaloside IV		0.9982	10–3000	10	99.7	6.9
Formononetin		0.9958	0.075–75	0.075	99.2	4.4
Cryptotanshinone		0.9916	0.075–75	0.075	98.3	4.4
Tanshinone IIA		0.9975	0.3–300	0.3	101	3.5