Pharmacokinetics of Caffeic Acid, Ferulic Acid, Formononetin, Cryptotanshinone, and Tanshinone IIA after Oral Administration of Naoxintong Capsule in Rat by HPLC-MS/MS

Table 3

Intraday and interday accuracy and precision of eleven compounds ().

Compounds	Concentration (ngmL^−1)	Intraday		Interday
		Accuracy (%)	RSD (%)	Accuracy (%)	RSD (%)
Paeoniflorin	7.5	93.0	14	95.7	2.5
	75	101	8.7	102	3.8
	750	96.6	6.3	101	1.2
Ecdysterone	15	111	8.4	102	2.5
	150	106	12	99.6	3.0
	1500	101	6.7	97.7	5.2
Amygdalin	30	98	10	101	1.9
	300	100	11	99.1	3.5
	3000	102	11	101	0.8
Mulberroside A	30	88	13	96.6	2.4
	300	104	12	90.9	8.3
	3000	114	3	98.8	12
Caffeic acid	30	103	8.5	102	3.0
	300	85	9.4	95.2	10
	3000	103	7.8	95.0	4.2
Ferulic acid	15	106	10	98.0	10
	150	111	7.7	102	7.0
	1500	113	2.9	106	4.5
Salvianolic acid B	30	103	10	97.2	9.4
	300	109	6	102	4.1
	3000	100	12	106	9.0
Astragaloside IV	30	90.3	14	94.7	4.9
	300	107	10	102	8.2
	3000	103	8.4	101	4.8
Formononetin	0.75	107	3.4	100	1.1
	7.5	105	14	101	8.2
	75	114	7.3	101	1.7
Cryptotanshinone	3	90	9.4	97.9	3.2
	30	97.4	14	101	13
	300	103	11	103	5.5
Tanshinone IIA	0.75	104	6.1	100	2.4
	7.5	101	15	98.7	5.8
	75	104	13	97.5	4.4