Antiobesity Effect of Astilbe chinensis Franch. et Savet. Extract through Regulation of Adipogenesis and AMP-Activated Protein Kinase Pathways in 3T3-L1 Adipocyte and High-Fat Diet-Induced C57BL/6N Obese Mice

Figure 3

The effect of Astilbe chinensis Franch. et Savat. (AC) extract on gene expression in 3T3-L1 adipocytes. (a) Expression of AMPK, ACC phosphorylation, (b) PGC-1α, PPARα and (c) ATGL, p-HSL mRNA and protein activated in the 3T3-L1 adipocytes and normalized by western blot (upper) and real-time PCR (lower). Data are presented as the mean ± SEM of three independent experiments, each performed in triplicate. < 0.05, < 0.01, and < 0.001 compared with differentiated cells (DM).

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