Research Article
Isolation and Biological Evaluation of Prenylated Flavonoids from Maclura pomifera
Table 4
Inhibition of recombinant human monoamine oxidase-A and monoamine oxidase-B of I–VIII from M. pomifera.
| | Compounds | Monoamine oxidase-A IC50 (μM) | Monoamine oxidase-B
IC50 (μM) | SI index
MAO-A/B |
| | Kazosajin I | | | 6.413 | | Kazosajin II | | | 16.829 | | Kazosajin III | >100 | | - | | Kazosajin IV | | | 4.032 | | Pomiferin (V) | >100 | >100 | - | | Auriculasin (VI) | | | 24.073 | | Warangalone (VII) | >100 | | - | | Osajin (VIII) | >100 | >100 | - | | Clorgyline | | - | - | | Deprenyl | - | | - |
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Notes. The results of IC50 values are expressed as mean ±SD of triplicate observations.
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