In Vivo Anticancer Activity of Basella alba Leaf and Seed Extracts against Ehrlich's Ascites Carcinoma (EAC) Cell Line

Figure 7

Agarose gel electrophoresis of extracted DNA, RNA, and PCR product from EAC cells treated with B. alba leaf and seed extracted and from control. Lane (M), (1), (2), and (3) represent as molecular marker, control, leaf treated, and seed treated, respectively. (a) Agarose gel electrophoresis of EAC cell’s DNA for both control and treated mice which showed distinct band for control and smear for treated mice’ mRNA. (b) The total RNA exhibited two different bands for both control and treated mice. (c) Expression of GAPDH in case of both control and treated EAC cells. (d) Upregulation of P⁵³genes in treated cells in compare to control. (e) Downregulation of Bcl-2 gene in case of treatment compared to control.

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