Qi-Dong-Huo-Xue-Yin Inhibits Inflammation in Acute Lung Injury in Mice via Toll-Like Receptor 4/Caveolin-1 Signaling

Figure 6

Regulation of the balance between serum pro- and anti-inflammatory cytokine levels by QDHXY in mice with LPS-induced ALI. Mice were pretreated with QDHXY (0.4 or 0.8 g) or dexamethasone (0.1 mg) daily for 6 days, after which they were treated with 50 μL of 1 mg/mL LPS. The five groups were, respectively, labeled as normal control, ALI, ALI + LDQ (LPS and low-dose QDHXY), ALI + HDQ (LPS and high-dose QDHXY), and ALI + DEX (LPS and dexamethasone). The serum ratios of (a) IL-6 to IL-10 and (b) GM-CSF to IL-13 were calculated. All data are ratios of the normal control and expressed as mean ± SD of three independent experiments. # indicates < 0.01 and ## indicates < 0.05 when compared to the normal control and ALI groups, respectively.

(a)

(b)