Establishment and Validation of an In Vitro Screening Method for Traditional Chinese Medicine-Induced Nephrotoxicity

Figure 2

Aristolochic acid (AA), cyclosporine A (CsA), and cisplatin (CDDP) dose-response curves for cell viability (a), mitochondrial mass (b), mitochondrial membrane potential (c), nuclear area (d), and nuclear roundness (e). HEK293 cells were exposed to 0.01, 0.1, 1, 10, and 100 μM of the three drugs. Data are means ± SEM ( = 4).

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