Establishment and Validation of an In Vitro Screening Method for Traditional Chinese Medicine-Induced Nephrotoxicity

Table 4

Pathological changes associated with acute toxicity.

Group	Death/total animals	Abnormalities
Control	0/6	Normal
Aristolochic acid (AA)	0/8	Rats have dark yellow hair
Cisplatin (CDDP)	3/8	Rats have dark yellow hair, dispirited
Diosbulbin B (DB)	0/9	Rats have dark yellow hair
Cantharidin (CA)	0/9	Rats have dark yellow hair
Triptolide (TR)	3/9	Rats have dark yellow hair, dispirited, huddle up
Sophocarpine (SC)	0/9	Rats have dark yellow hair