Research Article

Astragaloside Inhibits Hepatic Fibrosis by Modulation of TGF-β1/Smad Signaling Pathway

Figure 3

Astragaloside blocks the activation of HSC induced by TGF-β1. (a) By assay of ELISA, AST was found to decrease the expression of α-SMA. The expression of α-SMA was also assessed by real-time PCR (b) and western blot (c), normalized by β-actin. AST: astragalosides; LY-364947: TGF-β receptor 1 inhibitor. The values presented are the means ± SD ( in each group). and versus control group; and versus model group (TGF-β1).
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