Efficacy and Safety of Wei Bi Mei, a Chinese Herb Compound, as an Alternative to Bismuth for Eradication of Helicobacter pylori
Table 4
Serum biochemical values in rats orally treated with CBS at withdrawal at 0, 4, 8, and 12 weeks after bismuth exposure.
Parameter
Time
0
4 w
8 w
12 w
CBS
Water
CBS
Water
CBS
Water
CBS
Water
ALT (U/L)
40 (8)
38 (3)
46 (6)
47 (6)
39 (4)
41 (6)
42 (6)
42 (3)
AST (U/L)
84 (13)
134 (23)
131 (40)
116 (29)
98 (25)
82 (10)
123 (22)
109 (21)
ALP (U/L)
187 (54)
183 (67)
202 (31)
207 (50)
209 (47)
153 (31)
151 (29)
172 (77)
GLU (mmol/L)
5.4 (0.4)
5.2 (0.4)
5.90 (0.8)
5.6 (0.5)
5.5 (0.6)
5.2 (0.3)
5.1 (0.4)
5.4 (0.4)
TP (g/L)
53 (3)
56 (3)
54 (2)
55 (3)
53 (3)
57 (4)
54 (2)
54 (3)
ALB (g/L)
30 (1)
29 (2)
27 (2)
28 (3)
28 (3)
27 (2)
27 (2)
30 (2)
T-BIL (µmol/L)
8.36 (0.93)
7.26 (1.96)
8.13 (1.06)
6.68 (1.25)
7.58 (1.60)
7.95 (1.01)
7.4 (1.29)
7.47 (1.38)
D-BIL (µmol/L)
5.36 (0.93)
4.6 (1.32)
4.96 (1.07)
4.06 (0.72)
4.05 (1.06)
5.28 (0.49)
4.02 (0.64)
4.08 (0.96)
Cre (µmol/L)
38 (7)
40 (3)
34 (4)
33 (8)
30 (5)
33 (6)
36 (4)
37 (4)
Bun (mmol/L)
5.56 (1.01)
6.00 (1.26)
6.96 (1.42)
6.57 (0.98)
6.43 (0.97)
7.28 (2.47)
5.80 (0.51)
6.38 (1.16)
Na+ (mmol/L)
143 (2.3)
144 (2.0)
140 (1.50)
144 (1.73)
142 (2.3)
142 (2.5)
142 (2.3)
139 (1.4)
K+ (mmol/L)
4.43 (0.56)
4.31 (0.43)
4.37 (0.70)
4.59 (0.47)
4.75 (0.33)
4.30 (0.34)
4.21 (0.45)
4.56 (0.33)
Cl- (mmol/L)
98.4 (0.8)
97.7 (2.1)
98.1 (2.70)
96.5 (1.9)
99.2 (1.9)
96.8 (1.5)
101 (2.0)
100 (1.7)
Alanine aminotransferase activity (ALT), aspartate aminotransferase activity (AST), alkaline phosphatase activity (ALP), glucose (GLU), total protein (TP), albumin (ALB), total bilirubin (T-BIL), direct bilirubin (D-BIL), creatinine (CRE), blood urea nitrogen (BUN), potassium ions (K+), sodium ions (Na+), chloride ions (Cl-). Colloidal bismuth subcitrate (CBS); values are mean (SD); and when compared to the controls using the independent -test.
