Research Article

Efficacy and Safety of Wei Bi Mei, a Chinese Herb Compound, as an Alternative to Bismuth for Eradication of Helicobacter pylori

Table 5

Bismuth accumulation in kidney, heart, liver, and brain.

Wei Bi MeiBismuth aluminateCBS

Kidney
Lavage 8 w785.9 (14.6)3268.0 (205)18205 (506)<0.001
Lavage 8 w withdraw 4 w192.9 (6.67)269.5 (14.8)3399 (189)<0.001
Lavage 8 w withdraw 8 w37.7 (4.97)63.4 (5.67)315 (28.5)<0.001
Lavage 8 w withdraw 12 w3.73 (1.51)14.4 (1.81)91.4 (6.63)<0.001
Heart
Lavage 8 w5.43 (1.82)52.4 (2.53)73.6 (4.80)<0.001
Lavage 8 w withdraw 4 w2.19 (0.89)8.32 (1.14)28.2 (4.93)<0.001
Lavage 8 w withdraw 8 w1.93 (0.94)6.03 (1.44)10.0 (2.42)<0.001
Lavage 8 w withdraw 12 w0.98 (0.40)1.04 (0.45)1.00 (0.69)0.552
Liver
Lavage 8 w16.8 (2.22)102.8 (3.05)398 (5.70)<0.001
Lavage 8 w withdraw 4 w2.22 (1.16)7.65 (2.11)66.0 (2.39)<0.001
Lavage 8 w withdraw 8 w4.55 (1.39)4.97 (1.20)44.5 (6.60)<0.001
Lavage 8 w withdraw 12 w1.29 (0.63)1.47 (0.54)7.05 (2.56)<0.001
Brain
Lavage 8 w5.14 (0.81)95.6 (1.99)120.3 (4.97)<0.001
Lavage 8 w withdraw 4 w4.69 (2.50)10.2 (2.94)17.2 (3.65)<0.001
Lavage 8 w withdraw 8 w4.55 (1.39)4.97 (1.20)14.3 (1.58)<0.001
Lavage 8 w withdraw 12 w1.29 (0.65)4.46 (2.13)5.36 (2.26)0.004

CBS: colloidal bismuth subcitrate; values are mean (SD). 2One-way ANOVA was used to compare the values of three groups.