Evidence-Based Complementary and Alternative Medicine

Research Article

Association Rule Analysis for Validating Interrelationships of Combined Medication of Compound Kushen Injection in Treating Colon Carcinoma: A Hospital Information System-Based Real-World Study

Table 4

Frequency of pharmacological mechanisms of modern medicines combined with CKI (Top 20, N=3328).
Frequency sequencePharmacological mechanismDistribution frequency (%)Frequency sequencePharmacological mechanismDistribution frequency (%)
1Antineoplastic chemotherapeutic drugs2760 (82.93)11Painkiller1030 (30.95)
2Immunomodulator2308 (69.35)12Tranquilizer947 (28.46)
3Antibiotics1676 (50.36)13Medicine for electrolyte balance adjustment851 (25.57)
45-HT receptor antagonist drugs1658 (49.82)14Anesthetic799 (24.01)
5Nutritious drugs1386 (41.65)15Diuretics786 (23.62)
6Hepatic protector1303 (39.15)16H2 receptor antagonist drugs755 (22.69)
7Proton pump inhibitor1243 (37.35)17Analgesic and anti-inflammatory drugs668 (20.07)
8Antifolate1211 (36.39)18Cell differentiation drugs607 (18.24)
9Corticosteroids1152 (34.62)19Antianemics603 (18.12)
10Dopamine receptor antagonist1063 (31.94)20Expectorant557 (16.74)