α-Mangostin Alleviated Lipopolysaccharide Induced Acute Lung Injury in Rats by Suppressing NAMPT/NAD Controlled Inflammatory Reactions

Figure 2

Regulation of MAN on NAMPT and Sirt1 in vivo. (a) Expression of iNAMPT in lung; (b) expression of Sirt1 in lung; (c) quantitative results of immunohistochemical assays; (d) levels of eNAMPT in serum. Photographs A-D represent normal control, ALI model, MAN treated (low), and MAN treated (high), respectively. Statistical significance: < 0.01 compared with ALI models.

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