α-Mangostin Alleviated Lipopolysaccharide Induced Acute Lung Injury in Rats by Suppressing NAMPT/NAD Controlled Inflammatory Reactions

Figure 3

Regulation of MAN on NAMPT and Sirt1 in RAW 264.7 cells in vitro. (a) Expression of iNAMPT in cells; (b) levels of eNAMPT in culture medium; (c) expression of Sirt1 in cells; (d) deacetylation capability of Sirt1 indicated by expression of ace-p65 in cells. Statistical significance: < 0.05 and < 0.01 compared with LPS treated cells.

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