Interspecies Anticancer and Antimicrobial Activities of Genus Solanum and Estimation of Rutin by Validated UPLC-PDA Method

Figure 4

Molecular docking of rutin with human DNA Topoisomerase IIα. (A) Binding of rutin at the ATP-binding site of Topoisomerase IIα. (B) Molecular interaction of rutin with the residues of Topoisomerase IIα. (C) Ribbon representation of the binding between rutin and Topoisomerase IIα.