Anti-Inflammatory and Antioxidant Properties of the Extract, Tiliroside, and Patuletin 3-O-β-D-Glucopyranoside from Pfaffia townsendii (Amaranthaceae)

Figure 2

Effect of ethanolic extract of Pfaffia townsendii (EEPT) and isolated flavonoids on carrageenan-induced paw edema in mice. Animals received ethanol extract, EEPT, (300 mg/kg, p.o), tiliroside (1.0 mg/kg), patuletin 3-O-β-D-glucopyranoside (1.0 mg/kg), and dexamethasone (Dexa – 1.0 mg/kg, s.c.) or control (vehicle) and after 0.5 (a), 1 (b), 2 (c), and 4 hours (d), an intraplantar injection of carrageenan (300μg/paw) was performed. Each bar or point represents ± SEM of 6 animals. P < 0.05, P < 0.01, and P < 0.001, compared with vehicle-treated group.

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