Drug-Repositioning Approach for the Discovery of Anti-Influenza Virus Activity of Japanese Herbal (Kampo) Medicines<i> In Vitro</i>: Potent High Activity of Daio-Kanzo-To

<div>Cell-based screening of anti-influenza virus activity from Kampo medicines. Kampo medicines were tested to determine their anti-influenza virus activities using the herbal medicine library. Diluted Kampo medicines (closed boxes; 100 <i>μ</i>g/mL, open boxes; 10 <i>μ</i>g/mL) or oseltamivir (striped box; 41 <i>μ</i>g /mL, gray box; 4.1 <i>μ</i>g /mL) were added to MDCK cells in the presence of influenza virus A/WSN/33 and incubated for 48 h. The cells were fixed and stained with CV. Kampo medicines with antiviral activities &gt; 30% were considered to be positive results. Average values and standard deviation from two independent experiments are shown.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 1

Figure 1: Drug-Repositioning Approach for the Discovery of Anti-Influenza Virus Activity of Japanese Herbal (Kampo) Medicines<i> In Vitro</i>: Potent High Activity of Daio-Kanzo-To 

Figure 1 | Drug-Repositioning Approach for the Discovery of Anti-Influenza Virus Activity of Japanese Herbal (Kampo) Medicines In Vitro: Potent High Activity of Daio-Kanzo-To 