Curative Anti-Inflammatory Properties of Chinese Optimized Yinxieling Formula in Models of Parkinson’s Disease

Table 3

Profile 5 pathway enrichment.

	Pathway	DEGs genes with pathway annotation (105)	All genes with pathway annotation (7226)	P-value
1	Retinol metabolism	8 (7.62%)	86 (1.19%)	0.000032
2	Cytokine-cytokine receptor interaction	12 (11.43%)	264 (3.65%)	0.000416
3	Complement and coagulation cascades	6 (5.71%)	88 (1.22%)	0.001686
4	Cell adhesion molecules (CAMs)	8 (7.62%)	160 (2.21%)	0.002193
5	Natural killer cell mediated cytotoxicity	7 (6.67%)	136 (1.88%)	0.003526
6	Phototransduction	3 (2.86%)	28 (0.39%)	0.007502
7	Hematopoietic cell lineage	5 (4.76%)	92 (1.27%)	0.010664
8	Drug metabolism-cytochrome P450	4 (3.81%)	64 (0.89%)	0.013728
9	Tyrosine metabolism	3 (2.86%)	36 (0.5%)	0.015038
10	Glycolysis/Gluconeogenesis	4 (3.81%)	69 (0.95%)	0.017682
11	Pancreatic secretion	5 (4.76%)	106 (1.47%)	0.018754
12	Fatty acid degradation	3 (2.86%)	47 (0.65%)	0.030463
13	Arachidonic acid metabolism	4 (3.81%)	83 (1.15%)	0.032257
14	Steroid hormone biosynthesis	4 (3.81%)	85 (1.18%)	0.034777
15	Phagosome	6 (5.71%)	170 (2.35%)	0.036951
16	Renin secretion	3 (2.86%)	69 (0.95%)	0.078539
17	Renin-angiotensin system	2 (1.9%)	33 (0.46%)	0.082549
18	Leukocyte transendothelial migration	4 (3.81%)	114 (1.58%)	0.083811
19	Salivary secretion	3 (2.86%)	77 (1.07%)	0.101104
20	Olfactory transduction	21 (20%)	1094 (15.14%)	0.106036