Shenqi Fuzheng Injection Reverses Cisplatin Resistance through Mitofusin-2-Mediated Cell Cycle Arrest and Apoptosis in A549/DDP Cells

Figure 3

Downregulation of Mfn2 with increased cisplatin resistance in A549/DDP cells. (a) The expression level of Mfn2 in A549 and A549/DDP cells was measured by Western blot analysis and quantified by densitometry. Mean ± standard deviation, n = 3. (b and c) A549/DDP cells were cultured for 0, 24, and 48 hours in the absence or presence of cisplatin (40 μg/mL). The expression level of Mfn2 was measured by Western blot and immunocytochemical assays. A demiquantization value by densitometry is shown on the right.

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