Antiosteoarthritic Effects of ChondroT in a Rat Model of Monosodium Iodoacetate-Induced Osteoarthritis

Figure 5

Histopathological changes (safranin O-fast staining) in the knee joint after ChondroT administration in monosodium iodoacetate- (MIA-) induced arthritic rats. Several shrunken nuclei (arrows ↓) were observed in the MIA control. JC, joint cavity; AC, articular cartilage; SB, spongy bone. MIA-induced arthritic rats were orally given water (control), Joins Tab (20 mg/kg), or ChondroT (50, 100, or 200 mg/kg). Scale bars = 100 μm.

(a) Normal

(b) Control

(c) Joins Tab

(d) ChondroT 50

(e) ChondroT 100

(f) ChondroT 200