Research Article

The Influence of BuqiHuoxueTongluo Formula on Histopathology and Pulmonary Function Test in Bleomycin-Induced Idiopathic Pulmonary Fibrosis in Rats

Table 1

Histopathologic data of each group on two time points were presented as mean ± SD. Compared with control group (). Compared with BLM group (). Compared with BLM group (). Compared with BLM + Pred group (). Compared with BLM + Pred group ().

GroupAshcroft ScoreIOD of MassonIOD of TGF-IOD of α-SMA

14 d
 Control0.62 ± 0.528581.13 ± 632.7524995.82 ± 3563.9921832.67 ± 1966.80
 BLM4.50 ± 0.926115.82 ± 1540.8100346.48 ± 6601.192278.94 ± 6193.4
 BLM + Pred3.25 ± 0.817258.61 ± 1154.460129.47 ± 4257.664913.49 ± 6535.4
 BLM + BHTF3.13 ± 0.616475.62 ± 708.457401.83 ± 4382.666209.60 ± 5216.2
28 d
 Control0.63 ± 0.7414762.36 ± 3044.9624366.61 ± 2182.5125638.46 ± 2772.93
 BLM6.88 ± 0.8126988.62 ± 8401.0130333.38 ± 4003.7125050.03 ± 7026.0
 BLM + Pred4.38 ± 0.967266.04 ± 5606.969582.41 ± 5244.267740.38 ± 4371.7
 BLM + BHTF3.25 ± 0.757101.18 ± 4749.862756.15 ± 5155.862033.93 ± 4921.2