Sirt1/Foxo Axis Plays a Crucial Role in the Mechanisms of Therapeutic Effects of Erzhi Pill in Ovariectomized Rats

Figure 6

EZP upregulated mRNA expressions of Sirt1, Runx2, Foxo1, and Foxo3a and downregulated mRNA expression of PPAR-γ. Results of real-time PCR show the mRNA expressions of Sirt1 (a), Runx2 (b), Foxo1 (c), Foxo3a (d), and PPAR-γ (e) affected by EZP administration. GAPDH was used as the internal control for the quantification analysis. Data are the means ± standard deviation (SD) and SD is shown as vertical bars. means P<0.05; means P<0.01.

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