Vaccinium macrocarpon Aiton Extract Ameliorates Inflammation and Hyperalgesia through Oxidative Stress Inhibition in Experimental Acute Pancreatitis

Figure 2

Effect of the hydroethanolic extract of fruits of Vaccinium macrocarpon (HEVm) on pancreatic and lung myeloperoxidase (MPO) activity. Mice were submitted to injection of L-arginine or saline, treated with HEVm (50, 100, or 200 mg/kg), dexamethasone (Dexa; 5 mg/kg), or vehicle (saline), and euthanized after pancreatitis induction. MPO activity was measured in pancreas (a) and lung (b) tissues (-6). versus vehicle + saline and or versus vehicle + L-arginine. One-way ANOVA followed by Bonferroni’s test.

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(b)