Compound Phyllanthus urinaria L Inhibits HBV-Related HCC through HBx-SHH Pathway Axis Inactivation

Figure 7

CP could inhibit tumors growth in vivo. We transplanted the HepG2-NC cells and HepG2-HBx cells into Babl/c nude mice, respectively. Body weights (a) and tumor volume (b, e) were measured at the indicated times. We measured the tumor/weight (%) (c) and tumor inhibition rate (%) (d) at the end of experiment. < 0.001, compared with the group of HepG2-NC; ^#P < 0.05, ^##P < 0.01, and ^###P < 0.001, compared with the group of HepG2-HBx.

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(b)

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