Evidence-Based Complementary and Alternative Medicine

Research Article

Hypoglycemic Activity of Medicinal Plants Used among the Cakchiquels in Guatemala for the Treatment of Type 2 Diabetes

Table 1

Blood glucose levels under a normal curve.
  Glucose levels in the normal curve [mg/dl]
Group/time (min.)T0T30T60T90
Normal control108 ± 3 
100%		116 ± 4 
107%		114 ± 4 
106%		102 ± 2 
94%
Hyperglycemic control192 ± 6 
100%		184 ± 5 
96%		179 ± 4 
93%		187 ± 6 
97%
Hyperglycemic + glibenclamide 
5 mg/kg.		189 ± 4 
100%		117 ± 4 
62%		105 ± 3 
56%		106 ± 4 
56%
Croton guatemalensis W 
20 mg/kg		176 ± 4 
100%		163 ± 3 
93%		150 ± 5 
85%		142 ± 2 
81%
Croton guatemalensis EW 
30 mg/kg		181 ± 4 
100%		157 ± 10 
87%		123 ± 9 
68%		105 ± 5 
58%
Hamelia patens W  
36 mg/kg		201 ± 6 
100%		172 ± 5 
86%		156 ± 5 
78%		143 ± 5 
71%
Hamelia patens EW  
35 mg/kg		173 ± 1 
100%		162 ± 5 
94%		141 ± 4 
82%		141 ± 3 
82%
Neurolaena lobata W 
40 mg/ Kg		191 ± 3 
100%		152 ± 56 
80%		132 ± 5 
69%		139 ± 4 
73%
Neurolaena lobata EW 
57 mg/ Kg		186 ± 3 
100%		174 ± 4 
94%		156 ± 4 
84%		153 ± 5 
82%
Solanum americanum W 
62 mg/kg		191 ± 5 
100%		160 ± 6 
84%		138 ± 3 
72%		139 ± 3 
73%
Solanum americanum EW 
77 mg/kg		174 ± 2 
100%		163 ± 3 
94%		134 ± 3 
77%		127 ± 2 
73%
The values represent the mean ± SEM; in the same row: a indicates statistically significant differences compared with time 0; in the same column: b indicates statistically significant differences compared with the diabetic control group; p < 0.05, n=6.