Research Article

Hypoglycemic Activity of Medicinal Plants Used among the Cakchiquels in Guatemala for the Treatment of Type 2 Diabetes

Table 3

Blood glucose levels under a sucrose curve.

Glucose levels in the sucrose curve [mg/dl]

Group/time (min.)T0T30T60T90

Normal control114 ± 4 
100%
157 ± 2
138%
159 ± 5
139%
148 ± 5
130%

Hyperglycemic control179 ± 4 
100%
270 ± 21
151%
252 ± 29
141%
238 ± 27
133%

Hyperglycemic + acarbose 
3 mg/kg
182 ± 7 
100%
190 ± 8
104%
173 ± 6
95%
178 ± 6
98%

Croton guatemalensis W 
30 mg/kg
180 ± 5 
100%
215 ± 13
119%
189 ± 4
105%
165 ± 5
92%

Hamelia patens W 
36 mg/kg
171 ± 2 
100%
198 ± 5
116%
185 ± 10
108%
169 ± 3
99%

Solanum americanum W 
62 mg/kg
174 ± 4 
100%
225 ± 13
129%
182 ± 9
105%
153 ± 5
88%

Neurolaena lobata W 
40 mg/kg
172 ± 6 
100%
225 ± 10
131%
198 ± 16 
115%
161 ± 6
94%

The values represent the mean ± SEM. In the same row: a indicates statistically significant differences compared with time 0. In the same column: b indicates statistically significant differences compared with the diabetic control group; p < 0.05, n=6.