Apoptotic Effects of Xanthium strumarium via PI3K/AKT/mTOR Pathway in Hepatocellular Carcinoma

Figure 1

Effects of XS-5 and XS-6 on the growth and proliferation of HCC cells. (a) Cytotoxic effects of XS extracts on Huh-7 cells were measured using an MTT assay. (b) Hep3B and Huh-7 cells were treated with XS-5 and XS-6 at the indicated concentration for 72 h, and the cytotoxic effects were measured with an MTT assay. (c) Proliferation of Hep3B and Huh-7 cells was assessed using a BrdU proliferation assay. Results are expressed as percentage of cell proliferation relative to that of the control. Data are represented as means ± SD of triplicates (, , and vs control).

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