Protective Effects of Evodiamine against LPS-Induced Acute Kidney Injury through Regulation of ROS-NF-<i>κ</i>B-Mediated Inflammation

<div><i>Effects of EVO on functional injury of kidney in rats and cell viability in NRK-52E cells treated by LPS.</i> Rats were intraperitoneally (i.p.) injected with EVO (10 and 20 mg/kg) 1 h after LPS treatment. Kidney function was evaluated by the determination of blood urea nitrogen (BUN) (a) and creatinine (b) levels. NRK-52E cells were treated with 1 <i>μ</i>g/ml LPS in the presence or absence of 10 and 20 <i>μ</i>M EVO for 24h. Cell viability was detected by MTT assay (c). #p&lt;0.05 vs control group. ##p&lt;0.05 vs LPS group.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 2

Figure 2: Protective Effects of Evodiamine against LPS-Induced Acute Kidney Injury through Regulation of ROS-NF-<i>κ</i>B-Mediated Inflammation 

Evidence-Based Complementary and Alternative Medicine

Protective Effects of Evodiamine against LPS-Induced Acute Kidney Injury through Regulation of ROS-NF-κB-Mediated Inflammation

Figure 2