Therapeutic Efficiency of an External Chinese Herbal Formula of Mammary Precancerous Lesions by BATMAN-TCM Online Bioinformatics Analysis Tool and Experimental Validation

Figure 7

RYNXT significantly inhibited the protein expression of ER-α, PR, EGFR, COX2, and Src in MCF-10AT cells. (a) Western-blot assays of key protein expression at 24 h after vehicle, TAM, or various concentrations of RYNXT treatment in MCF-10AT cells. (b) Relative protein expression of ER-α, PR, EGFR, COX2, and Src in (a). P<0.05, RYNXT (2%; 4%), TAM, or Veh versus group control group; ^▲P<0.05, RYNXT (2%; 4%), TAM, or control group versus Veh group. Data are representative of 3 independent experiments.

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