Research Article

Antihyperlipidemic and Antioxidative Potentials of Onion (Allium cepa L.) Extract Fermented with a Novel Lactobacillus casei HD-010

Table 5

Effect of fermented onion with L. casei HD-010 on serum triglyceride level in ApoE-deficient mice.

TreatmentDose 
(mg/kg/day)
Triglyceride (TG, mg/ dl)
0 weeks1 week2 weeks3 weeks4 weeks5 weeks6 weeks

Control0406.6±35.68561.2±54.01334.4±60.37652.3±65.16302.3±48.56412.2±75.99284.8±54.11
Low25379.1±76.36553.5±70.59301.0±75.14628.2±63.90288.3±45.88396.2±59.68266.6±23.08
Mid50363.5±64.19461.6±99.73270.1±16.91581.1±34.41283.1±43.47321.0±82.27265.7±16.24
High100395.5±61.04449.7±59.96228.5±42.10537.3±62.24273.4±60.84241.5±68.03252.5±39.91
L. casei KCTC 2180100410.4±78.77475.9±41.84275.2±37.67507.0±24.04241.7±57.09255.9±65.39270.3±26.89
Benzafibrate10380.5±86.76529.5±90.37285.3±52.13656.7±71.61257.2±33.35396.9±99.12273.6±39.73

Data are presented as mean ± SD (10 animals per group; three independent experiments were performed).
Statistical significance between control and treated values was determined by two-tailed Student’s t-testand is given as a p value; p value < 0.05 and p value < 0.001.