Antihyperlipidemic and Antioxidative Potentials of Onion (Allium cepa L.) Extract Fermented with a Novel Lactobacillus casei HD-010
Table 5
Effect of fermented onion with L. casei HD-010 on serum triglyceride level in ApoE-deficient mice.
Treatment
Dose (mg/kg/day)
Triglyceride (TG, mg/ dl)
0 weeks
1 week
2 weeks
3 weeks
4 weeks
5 weeks
6 weeks
Control
0
406.6±35.68
561.2±54.01
334.4±60.37
652.3±65.16
302.3±48.56
412.2±75.99
284.8±54.11
Low
25
379.1±76.36
553.5±70.59
301.0±75.14
628.2±63.90
288.3±45.88
396.2±59.68
266.6±23.08
Mid
50
363.5±64.19
461.6±99.73
270.1±16.91
581.1±34.41
283.1±43.47
321.0±82.27
265.7±16.24
High
100
395.5±61.04
449.7±59.96
228.5±42.10
537.3±62.24
273.4±60.84
241.5±68.03
252.5±39.91
L. casei KCTC 2180
100
410.4±78.77
475.9±41.84
275.2±37.67
507.0±24.04
241.7±57.09
255.9±65.39
270.3±26.89
Benzafibrate
10
380.5±86.76
529.5±90.37
285.3±52.13
656.7±71.61
257.2±33.35
396.9±99.12
273.6±39.73
Data are presented as mean ± SD (10 animals per group; three independent experiments were performed). Statistical significance between control and treated values was determined by two-tailed Student’s t-testand is given as a p value; p value < 0.05 and p value < 0.001.