The Pathogenicity and Transcriptome Analysis of Methicillin-Resistant Staphylococcus aureus in Response to Water Extract of Galla chinensis
Figure 1
Sensitivity of S. aureus to G. chinensis extract. (a) Morphology of dried Galla chinensis; (b) morphology of G. chinensis extract solutions; (c) the inhibition zone (the upper lane) and the minimum inhibitory concentration values (the lower lane) of G. chinensis extract solution for S. aureus; (d) crystal violet stain for methicillin-resistant S. aureus cells treated with different concentrations of G. chinensis extract for biomass comparison (p<0.05, n=10); (e) scanning electron microscopy (SEM) observation of the biofilm architecture of MRSA strain, MRSA treated with G. chinensis (1/2 MIC), and S. aureus ATCC with G. chinensis (1/2 MIC), respectively, at 24 h of growth. The MRSA biofilm treated with G. chinensis (1/2 MIC) presented a reduction in the extracellular matrices and only small microcolonies existing compared with untreated MRSA strains.