Enhancing the Therapeutic Efficacy of Daunorubicin and Mitoxantrone with Bavachinin, Candidone, and Tephrosin

Figure 1

Relative quantification of MDR protein expression levels by flow cytometer. The protein levels of ABCG2 and P-gp in MCF7/MX and EPG85.257RDB were, respectively, quantified in the presence of bavachinin, candidone, and tephrosin using flow cytometry. Fold changes were calculated relative to the untreated control, and the data are presented as the mean of triplicate experiments ± SEM. The symbols , , and represent values <0.05, <0.01, and <0.001, respectively. The Y-axis was plotted by log10 (a) and log2 (b).

(a)

(b)