Yiqihuoxue Formula Activates Autophagy and Offers Renoprotection in a Rat Model of Adenine-Induced Kidney Disease

<div>YQHX treatment improved the activation level of renal autophagy in the adenine rats. (a, b) Immunofluorescence staining was applied to detect the changes in LC3-II and p62 expression levels in the control, adenine, and YQHX groups. The puncta with green color indicates the autophagosomes represented by LC3-II, while the red ones indicate p62. The number of rats per group was 5, and 10 pictures were taken randomly from each rat. Scale bar: 20 <i>μ</i>m. 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(c) Results of the western blotting analysis of p62 and LC3-II. The high expression level of p62 was downregulated by the YQHX treatment. 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Evidence-Based Complementary and Alternative Medicine

fig5

Figure 5

Figure 5: Yiqihuoxue Formula Activates Autophagy and Offers Renoprotection in a Rat Model of Adenine-Induced Kidney Disease 