Glu-mGluR2/3-ERK Signaling Regulates Apoptosis of Hippocampal Neurons in Diabetic-Depression Model Rats

Figure 6

Changes in hippocampal expression of caspase-3, mGluR2/3, and ERK among model groups according to Western blot analysis. (a) Images of Western blots. (b) Densitometric quantitation. Results are presented as mean ± standard deviation (n=6 rats/group). A: control group; B: diabetes model group; C: depression-like model group; D: DD model group; E: LY341495+DD. p < 0.05, p < 0.01 vs. control; ^#p < 0.05, ^##p < 0.01 vs. diabetes group; ^Δp < 0.05, ^ΔΔ p < 0.01 vs. depression group; ^∧p < 0.05, ^∧∧p < 0.01 vs. DD group.

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(b)