Design, Preparation, and Characterization of Dioscin Nanosuspensions and Evaluation of Their Protective Effect against Carbon Tetrachloride-Induced Acute Liver Injury in Mice

Figure 13

Effect of Dio-NS on CCl4-induced hepatotoxicity. (a) The activities of ALTin the serum. (b) The activities of ASTin the serum. (c) The liver index. (d) The activities of TNF-a in the serum. (e) The activities of IL-1β in the serum. (f ) The activities of IL-6 in the serum. (g) The levels of MDA in the liver. (h) The levels of GSH-px in the liver. (i) The levels of SOD in the liver. ^∗∗P < 0.01 vs control, +P < 0.05, and ++P < 0.01 vs. model.

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