Antileishmanial Evaluation of the Leaf Latex of Aloe macrocarpa, Aloin A/B, and Its Semisynthetic Derivatives against Two Leishmania Species

Table 3

Selectivity indices of the test substances toward Leishmania aethiopica and Leishmania donovani.

Test substance	Selectivity index
	L. aethiopica	L. donovani
Latex	104.44	96.04
Aloin A/B	55.11	52.84
Aloe-emodin	65.22	52.89
Rhein	171.98	148.46
Amphotericin B (reference)	8.31	6.60
Media alone (NC)	0.00	0.00
1% DMSO (NC)	0.00	0.00

NC: negative control.