Research Article

Assessment of the Aromatase Inhibitory Activity of Ma-Huang-Tang (MHT) and Its Active Compounds

Table 2

Aromatase inhibitory effect of the main compounds from MHT components.

ConstituentChemical nameAromatase inhibition (IC50)Maximum con. (mM)

Ephedrae HerbaEphedrine (1)>10 mM10

Cinnamomi RamulusCoumarin (2)>10 mM10
Cinnamic acid (3)>10 mM10
Cinnamaldehyde (4)>10 mM10

Glycyrrhizae Radix et RhizomaLiquiritin (5)530 μM10
Liquiritin apioside (6)508 μM10
Liquiritigenin (7)1.611 mM10
Glycyrrhizin (8)>10 mM10