Nephroprotective Effect of Herbal Extract Eurycoma longifolia on Paracetamol-Induced Nephrotoxicity in Rats

Table 2

Effect of EL extract on serum total protein, serum albumin, serum urea, serum creatinine, creatinine clearance levels, and BUN/creatinine ratio.

	Experimental Group
	Control	PCM alone	EL 100	EL 200	EL 400
serum total protein (g/dl)	11.1±2.0	7.0±1.2^#	8.9±1.6	9.4±1.	10.1±1.
serum albumin (g/dl)	3.6±0.7	1.7±0.7^#	1.6±0.8	3.1±0.	3.1±0.
blood urea (mg/dl)	18.0±1.5	41.7±7.3^#	42.8±7.5	21.7±3.	18.0±2.
serum creatinine (mg/dl)	0.8±0.1	1.6±0.5^#	1.7±0.3	0.9±0.	0.8±0.
creatinine clearance (ml/min)	0.86±0.1	0.31±0.12^###	0.30±0.05	0.61±0.2	0.87±0.2
BUN/creatinine ratio	22.8	25.1	24.8	24.4	23.7

Data are mean ± SD; ^#p<0.05 and ^###p<0.001 in comparison to control; <0.05, <0.01, and <0.001 when compared to PCM alone.