Systems-Pharmacology-Based Identification of Antitumor Necrosis Factor Effect in Mimeng Flower Decoction for the Treatment of Diabetic Retinopathy

Figure 2

Systems pharmacology analysis of Mimeng flower decoction (MFD) in treating diabetic retinopathy (DR). (a) Meta-analysis of the efficacy of MFD in treating DR. (b) Screening active compounds in MFD. (c) Network of active compounds and the targets. Blue nodes represent active compounds, and orange nodes represent potential targets. The edge represents the interaction between them. (d) Overlap analysis of the targets of active compounds and DR-related genes. (e) Compound-target-disease network. The nodes represent the genes, and node size is proportional to its degree. The edges represent the interaction between genes, and edge size is proportional to the interaction score based on the STRING database. DL, drug-likeness; OB, oral bioavailability.

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