Research Article

Chinese Herbal Medicine Ameliorated the Development of Chronic Kidney Disease in Patients with Chronic Hepatitis C: A Retrospective Population-Based Cohort Study

Table 1

Characteristics of hepatitis patients with and without CHM.

CharacteristicCHM value
No
N = 2710
Yes
N = 2710
n (%)n (%)

Gender0.09
Female1094 (40.4)1033 (38.1)
Male1616 (59.6)1677 (61.9)

Age, year0.01
18–44926 (34.2)828 (30.6)
45–59873 (32.2)972 (35.9)
≥60911 (33.6)910 (33.6)
Mean (SD)53.2 (16.1)53.2 (14.58)0.97

Urbanization0.29
1 (highest)677 (25)646 (23.8)
2792 (29.2)835 (30.8)
3409 (15.1)437 (16.1)
4 (lowest)832 (30.7)792 (29.2)

Comorbidity
Hypertension1124 (41.5)1117 (41.2)0.85
Diabetes mellitus769 (28.4)751 (27.7)0.59
Coronary artery disease734 (27.1)723 (26.7)0.74
Hyperlipidemia789 (29.1)776 (28.6)0.7
Liver cirrhosis474 (17.5)457 (16.9)0.54
Heart failure123 (4.5)113 (4.2)0.51
Osteoporosis367 (13.5)359 (13.2)0.75
Arrhythmia310 (11.4)289 (10.7)0.36
PVD66 (2.4)65 (2.4)0.93

Medication
HBV drug121 (4.5)123 (4.5)0.9
HCV drug177 (6.5)165 (6.1)0.5
CKD drug1512 (55.8)1491 (55)0.57
DM drug467 (17.2)474 (17.5)0.8
Statin320 (11.8)315 (11.6)0.83

Chi-squared test; t-test. Abbreviations: CHM, Chinese herbal medicine; SD, standard deviation; PVD, peripheral vascular disease; HBV, hepatitis B virus; hepatitis C virus; CKD, chronic kidney disease; DM, diabetes mellitus.