Chinese Herbal Medicine Ameliorated the Development of Chronic Kidney Disease in Patients with Chronic Hepatitis C: A Retrospective Population-Based Cohort Study

Table 5

Hazard Ratios and 95% confidence intervals of CKD risk associated with cumulative use day of TCM among hepatitis patients.

	Event no.; (n = 770)	Person year	IR	Hazard ratio (95% CI)
				Crude	Adjusted^†
Non-TCM users	318	9069	3.51	1.00 (ref.)	1.00 (ref.)
Chinese herb users
30–60 days	144	4045	3.56	0.99 (0.81–1.20)	0.88 (0.72–1.07)
60–90 days	74	2253	3.28	0.91 (0.71–1.17)	0.82 (0.64–1.06)
>90 days	234	9236	2.53	0.70 (0.58–0.83)	0.58 (0.49–0.69)
for trend

Crude HR represented relative hazard ratio; adjusted HR^† represented adjusted hazard ratio: mutually adjusted with gender, age, urbanization, comorbidity, and medication in Cox proportional hazard regression. , , .