Chinese Herbal Medicine Ameliorated the Development of Chronic Kidney Disease in Patients with Chronic Hepatitis C: A Retrospective Population-Based Cohort Study
Table 7
Hazard ratios and 95% confidence intervals of mortality risk associated with herbal formulas among hepatitis patients.
TCM prescription
CKD
Hazard ratio (95% CI)
No. of events
Crude
Adjusted†
Non-TCM user
318
Ref.
Ref.
Single herb
Salviae Miltiorrhizae
201
0.92 (0.77–1.11)
0.73 (0.61–0.89)
Corydalis Rhizoma
194
0.87 (0.72–1.05)
0.74 (0.61–0.89)
Rhei Radix et Rhizoma
108
0.95 (0.76–1.18)
0.75 (0.60–0.95)
Scutellariae Radix
145
0.76 (0.62–0.94)
0.72 (0.58–0.89)
Astragali Radix
127
1.00 (0.81–1.24)
0.83 (0.67–1.03)
Fritillariae Thunbergii Bulbus
152
0.84 (0.69–1.03)
0.74 (0.60–0.91)
Platycodonis Radix
153
0.95 (0.78–1.15)
0.81 (0.66–0.99)
Puerariae Lobatae Radix
143
0.82 (0.67–1.00)
0.71 (0.58–0.88)
Polygoni Multiflori Thunb
93
0.80 (0.63–1.01)
0.69 (0.54–0.88)
Ziziphi Spinosae Semen
96
0.86 (0.68–1.08)
0.76 (0.59–0.96)
Formula
Jia-Wei-Xiao-Yao-San
150
0.85 (0.69–1.03)
0.80 (0.65–0.99)
Xiao-Chai-Hu Tang
165
0.87 (0.72–1.06)
0.74 (0.60–0.90)
Shu-jing-huo-xue-tang
196
0.91 (0.76–1.09)
0.75 (0.62–0.91)
Ban-Xia-Xie-Xin-Tang
145
0.96 (0.78–1.17)
0.82 (0.66–1.01)
Shao-Yao-Gan-Cao-Tang
162
0.80 (0.66–0.98)
0.69 (0.57–0.85)
Long-Dan-Xie-Gan-Tang
123
0.96 (0.77–1.19)
0.81 (0.65–1.01)
Suan-Zao-Ren-Tang
106
0.80 (0.64–1.01)
0.72 (0.57–0.91)
Xue-Fu-Zhu-Yu-Tang
144
0.91 (0.74–1.12)
0.75 (0.61–0.93)
Xiang-Sha-Liu-Jun-Zi-Tang
118
0.86 (0.69–1.06)
0.67 (0.54–0.84)
Ping-Wei-San
113
0.81 (0.65–1.01)
0.68 (0.54–0.85)
Crude HR represented relative hazard ratio; adjusted HR† represented adjusted hazard ratio: mutually adjusted for age group, gender, urbanization level, and cci score in Cox proportional hazard regression. ,,.
