Research Article

Acute and Subacute Toxicity of Methanol Extract of Syzygium guineense Leaves on the Histology of the Liver and Kidney and Biochemical Compositions of Blood in Rats

Table 2

Comparison of the effect of 80% methanol extract of the leaves of Syzygium guineense on body weight of treated and control rats during acute toxicity study.

ParametersDosesMean ± SEMSignificance

Body weight initial week 1Control5.63 ± 5.630.91
2000 mg/kg126.83 ± 3.14
5000 mg/kg125.33 ± 3.04

Body weight week 2Control134.90 ± 7.650.89
2000 mg/kg131.23 ± 3.08
5000 mg/kg131.78 ± 5.68

Body weight week 3Control146.93 ± 9.300.93
2000 mg/kg145.73 ± 5.49
5000 mg/kg143.10 ± 6.80

Values are expressed as mean ± SEM, N= 4/group.