Research Article

Acute and Subacute Toxicity of Methanol Extract of Syzygium guineense Leaves on the Histology of the Liver and Kidney and Biochemical Compositions of Blood in Rats

Table 4

Effect of 80% methanol extract of leaves of S. guineense on hematological parameters.

Hematological parametersDosesMean95% Confidence interval for meanP value
Lower boundUpper bound

WBC x103/μLControl8.307.099.51.384
500mg/kg8.137.239.03
1500mg/kg9.456.6712.23

RBC x 106/μLControl7.316.927.70.859
500mg/kg7.306.737.86
1500mg/kg7.436.997.86

HGB (g/dL)Control14.9813.7416.23.693
500mg/kg15.3514.7515.95
1500mg/kg15.4014.5016.30

HCT (%)Control48.8047.1450.46.814
500mg/kg49.1845.9052.47
1500mg/kg49.8046.5553.05

MCV (fL)Control66.8064.2669.34.887
500mg/kg67.4764.5970.34
1500mg/kg67.0565.1069.00

MCH (pg)Control20.5019.1021.90.618
500mg/kg21.1219.9922.25
1500mg/kg20.7519.9721.53

MCHC (g/dL)Control30.7328.0833.39.894
500mg/kg31.3029.5033.10
1500mg/kg30.9829.0232.95

PLT x 103/μLControl697.17603.01791.32.768
500mg/kg671.67577.80765.54
1500mg/kg713.17591.87834.47

One way ANOVA, n = 6/group.