Comparative Antidiabetic Activity of Aqueous, Ethanol, and Methanol Leaf Extracts of Persea americana and Their Effectiveness in Type 2 Diabetic Rats

Figure 4

Effect of P. americana leaf extracts on islets of Langerhans of type 2 diabetic rats after 28 consecutive days of treatment. Pancreas tissue section stained with hematoxylin-eosin (×400). (a) Nondiabetic control (NDC), normal islet; (b) diabetic control (DC), severe atrophy islet (SA); (c) GLIB (10 mg/kg), mild atrophy islet diameter composed of a small number of hyperchromatic nuclei; (d–f) diabetic rats treated, respectively, with AE, EE, and ME (100 mg/kg) extracts, regeneration of islets of Langerhans.

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