Comparative Antidiabetic Activity of Aqueous, Ethanol, and Methanol Leaf Extracts of Persea americana and Their Effectiveness in Type 2 Diabetic Rats

Figure 5

Effect of P. americana leaf extracts on kidney of type 2 diabetic rats after 28 consecutive days of treatment. Kidney tissue section stained with hematoxylin-eosin (×250 or 400). (a) Nondiabetic control (NDC), kidney tissue has distal and proximal convoluted tubule (DCT and PCT) of normal architecture. (b) Diabetic control (DC): kidney tissue without histological abnormality. (c) GLIB (10 mg/kg), renal tissues with glomeruli (G) normal appearance. (d–f) Diabetic rats treated, respectively, with AE, EE, and ME (100 mg/kg), kidney tissue without architectural anomaly with the presence of congestive vessel (GV).

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