Comparative Antidiabetic Activity of Aqueous, Ethanol, and Methanol Leaf Extracts of Persea americana and Their Effectiveness in Type 2 Diabetic Rats

Figure 6

Effect of P. americana leaf extracts on the liver of type 2 diabetic rats after 28 consecutive days of treatment. Liver tissue section stained with hematoxylin-eosin and Masson (×250 or 400). (a) Nondiabetic control (NDC), liver tissue no irregularity. (b) Diabetic control (DC), representative picture shows hepatocyte regular spans architecture without histological abnormality. (c) GLIB (10 mg/kg), normal liver architecture without fibrous lesion; (d–f) Diabetic rats treated, respectively, with AE, EE, and ME (100 mg/kg), hepatic parenchyma of normal architecture with a portal space compound of the hepatic artery (HA), hepatic vein (HV), and bile canaliculus (BC).

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