Research Article

Comparative Antidiabetic Activity of Aqueous, Ethanol, and Methanol Leaf Extracts of Persea americana and Their Effectiveness in Type 2 Diabetic Rats

Table 1

Organ to body weight ratio percentages for type 2 diabetic model rats treated for 28 consecutive days.

Ratio (%)Groups
NDC (n = 5)DC (n = 6)GLIB (10 mg/kg) (n = 6)AE (100 mg/kg) (n = 7)EE (100 mg/kg) (n = 7)ME (100 mg/kg) (n = 7)

Ratio kidney0.550 ± 0.0150.790 ± 0.0410.730 ± 0.0650.644 ± 0.0420.577 ± 0.0410.549 ± 0.011
Ratio liver2.70 ± 0.0703.78 ± 0.1833.15 ± 0.1783.47 ± 0.2502.97 ± 0.2292.786 ± 0.051

NDC: nondiabetic control group treated with vehicle; DC: diabetic control group treated with vehicle; GLIB: group treated with glibenclamide, 10 mg/kg; AE: group treated with aqueous extract, 100 mg/kg; EE: group treated with ethanol extract, 100 mg/kg; ME: group treated with methanol extract, 100 mg/kg. The values are expressed as mean ± SEM (n = 5–7). Statistically significant vs. NDC: ; .