Recognition and Optimization of Ingredients Treating Nitroglycerin-Induced Migraine Rats from Wuzhuyu Decoction

Figure 3

The pharmacodynamic results of uniform verification test. (a, b, c) The contents of monoamine neurotransmitters determined by electrochemical detector. (d, e) The contents of NO-b, NO-p determined by NO assay kit. (f) The Y calculated through the entropy-weighted partial least squares method. Data are shown as mean ± SEM (fold change of normal group). P < 0.05 and P < 0.01 versus Normal group; P < 0.05 and P < 0.01 versus Model group; ^◇P < 0.05 and ^◇◇P < 0.01 versus UNOS group; P < 0.05 and P < 0.01 versus UDS-10 group; P < 0.05 and P < 0.01 versus OS-1 group. Data were analysed by One-way ANOVA followed by least significant difference or Tambane’s T2 analysis (n = 6 animals per group).

(a)

(b)

(c)

(d)

(e)

(f)